IL-27p28 inhibits central nervous system autoimmunity by concurrently antagonizing Th1 and Th17 responses

Central nervous system (CNS) autoimmunity such as uveitis and multiple sclerosis is accompanied by Th1 and Th17 responses. In their corresponding animal models, experimental autoimmune uveitis (EAU) and experimental autoimmune encephalomyelitis (EAE), both responses are induced and can drive disease...

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Autores principales: Chong, Wai Po, Horai, Reiko, Mattapallil, Mary J., Silver, Phyllis B., Chen, Jun, Zhou, Ru, Sergeev, Yuri, Villasmil, Rafael, Chan, Chi-Chao, Caspi, Rachel R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975693/
https://ncbi.nlm.nih.gov/pubmed/24021664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2013.08.003
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