IL-27p28 inhibits central nervous system autoimmunity by concurrently antagonizing Th1 and Th17 responses

Central nervous system (CNS) autoimmunity such as uveitis and multiple sclerosis is accompanied by Th1 and Th17 responses. In their corresponding animal models, experimental autoimmune uveitis (EAU) and experimental autoimmune encephalomyelitis (EAE), both responses are induced and can drive disease...

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Hlavní autoři: Chong, Wai Po, Horai, Reiko, Mattapallil, Mary J., Silver, Phyllis B., Chen, Jun, Zhou, Ru, Sergeev, Yuri, Villasmil, Rafael, Chan, Chi-Chao, Caspi, Rachel R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975693/
https://ncbi.nlm.nih.gov/pubmed/24021664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2013.08.003
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