IL-27p28 inhibits central nervous system autoimmunity by concurrently antagonizing Th1 and Th17 responses

Central nervous system (CNS) autoimmunity such as uveitis and multiple sclerosis is accompanied by Th1 and Th17 responses. In their corresponding animal models, experimental autoimmune uveitis (EAU) and experimental autoimmune encephalomyelitis (EAE), both responses are induced and can drive disease...

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Main Authors: Chong, Wai Po, Horai, Reiko, Mattapallil, Mary J., Silver, Phyllis B., Chen, Jun, Zhou, Ru, Sergeev, Yuri, Villasmil, Rafael, Chan, Chi-Chao, Caspi, Rachel R.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975693/
https://ncbi.nlm.nih.gov/pubmed/24021664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2013.08.003
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