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The Living Eye “Disarms” Uncommitted Autoreactive T Cells by Converting Them to FoxP3(+) Regulatory Cells Following Local Antigen Recognition

Immune privilege is used by the eye, brain, reproductive organs and gut to preserve structural and functional integrity in the face of inflammation. The eye is arguably the most vulnerable, and therefore also the most “privileged” of tissues, but paradoxically, remains subject to destructive autoimm...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhou, Ru, Horai, Reiko, Silver, Phyllis B, Mattapallil, Mary J, Zárate-Bladés, Carlos R, Chong, Wai Po, Chen, Jun, Rigden, Rachael C, Villasmil, Rafael, Caspi, Rachel R
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273602/
https://ncbi.nlm.nih.gov/pubmed/22238462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102415
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