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A novel role for lipoxin A(4) in driving a lymph node–eye axis that controls autoimmunity to the neuroretina
The eicosanoid lipoxin A(4) (LXA(4)) has emerging roles in lymphocyte-driven diseases. We identified reduced LXA(4) levels in posterior segment uveitis patients and investigated the role of LXA(4) in the pathogenesis of experimental autoimmune uveitis (EAU). Immunization for EAU with a retinal self-...
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| Publié dans: | eLife |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
eLife Sciences Publications, Ltd
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7064344/ https://ncbi.nlm.nih.gov/pubmed/32118582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.51102 |
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