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Altered Chemokine Profile Associated with Exacerbated Autoimmune Pathology under Conditions of Genetic Interferon-γ Deficiency

PURPOSE: A prior study showed that mice deficient in IFN-γ (GKO) are more susceptible to experimental autoimmune uveitis (EAU) than are wild-type (WT) mice. Histopathology of uveitic eyes revealed that the ocular infiltrate in GKO mice was dominated by neutrophils and eosinophils rather than by mono...

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Bibliografiske detaljer
Main Authors: Su, Shao Bo, Grajewski, Rafael S., Luger, Dror, Agarwal, Rajeev K., Silver, Phyllis B., Tang, Jun, Tuo, Jingsheng, Chan, Chi-Chao, Caspi, Rachel R.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756241/
https://ncbi.nlm.nih.gov/pubmed/17898285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.07-0233
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