Non-proteinogenic amino acids in the pThr-2 position of a pentamer peptide that confer high binding affinity for the polo box domain (PBD) of polo-like kinase 1 (Plk1)

Por Qian, Wen-Jian, Park, Jung-Eun, Lee, Kyung S., Burke, Terrence R.
Publicado em 2012

Effects on Polo-like Kinase 1 Polo-box Domain Binding Affinities of Peptides Incurred by Structural Variation at the Phosphoamino Acid Position

Por Qian, Wenjian, Park, Jung-Eun, Liu, Fa, Lee, Kyung S., Burke, Terrence R.
Publicado em 2012

Probing Binding Modes of Small Molecule Inhibitors to the Polo-Box Domain of Human Polo-like Kinase 1

Por Liao, Chenzhong, Park, Jung-Eun, Bang, Jeong K., Nicklaus, Marc C., Lee, Kyung S.
Publicado em 2010

Synthesis and SAR of Thiazolylmethylphenyl Glucoside as Novel C-Aryl Glucoside SGLT2 Inhibitors

Por Song, Kwang-Seop, Lee, Suk Ho, Kim, Min Ju, Seo, Hee Jeong, Lee, Junwon, Lee, Sung-Han, Jung, Myung Eun, Son, Eun-Jung, Lee, MinWoo, Kim, Jeongmin, Lee, Jinhwa
Publicado em 2010

Optimizing Thiadiazole Analogues of Resveratrol vs. Three Chemopreventive Targets

Por Mayhoub, Abdelrahman S., Marler, Laura, Kondratyuk, Tamara, Park, Eun-Jung, Pezzuto, John M., Cushman, Mark
Publicado em 2011

Optimization of Thiazole Analogues of Resveratrol for Induction of NAD(P)H:quinone Reductase 1 (QR1)

Por Mayhoub, Abdelrahman S., Marler, Laura, Kondratyuk, Tamara P., Park, Eun-Jung, Pezzuto, John M., Cushman, Mark
Publicado em 2012

Structure-activity relationships and docking studies of synthetic 2-arylindole derivatives determined with aromatase and quinone reductase 1

Por Prior, Allan M., Yu, Xufen, Park, Eun-Jung, Kondratyuk, Tamara P., Lin, Yan, Pezzuto, John M., Sun, Dianqing
Publicado no Bioorg Med Chem Lett (2017)

Design, synthesis, and biological evaluation of callophycin A and analogues as potential chemopreventive and anticancer agents

Por Shen, Li, Park, Eun-Jung, Kondratyuk, Tamara P., Guendisch, Daniela, Marler, Laura, Pezzuto, John M., Wright, Anthony D., Sun, Dianqing
Publicado em 2011

Anti-AIDS Agents 81. Design, Synthesis and Structure-Activity Relationship Study of Betulinic Acid and Moronic Acid Derivatives as Potent HIV Maturation Inhibitors

Por Qian, Keduo, Kuo, Reen-Yun, Chen, Chin-Ho, Huang, Li, Morris-Natschke, Susan L., Lee, Kuo-Hsiung
Publicado em 2010

Selective Synthesis and Biological Evaluation of Sulfate-Conjugated Resveratrol Metabolites

Por Hoshino, Juma, Park, Eun-Jung, Kondratyuk, Tamara P., Marler, Laura, Pezzuto, John M., van Breemen, Richard B., Mo, Shunyan, Li, Yongchao, Cushman, Mark
Publicado em 2010

Cytotoxic cardiac glycosides and coumarins from Antiaris toxicaria

Por Shi, Li-Shian, Kuo, Sheng-Chu, Sun, Han-Dong, Morris-Natschke, Susan L., Lee, Kuo-Hsiung, Wu, Tian-Shung
Publicado no Bioorg Med Chem (2014)

Design and synthesis of 6,7-methylenedioxy-4-substituted phenylquinolin-2(1H)-one derivatives as novel anticancer agents that induce apoptosis with cell cycle arrest at G2/M phase

Por Chen, Yi-Fong, Lin, Yi-Chien, Huang, Po-Kai, Chan, Hsu-Chin, Kuo, Sheng-Chu, Lee, Kuo-Hsiung, Huang, Li-Jiau
Publicado em 2013

Potential Chemopreventive Agents Based on the Structure of the Lead Compound 2-Bromo-1-hydroxyphenazine, Isolated from Streptomyces sp., Strain CNS284

Por Conda-Sheridan, Martin, Marler, Laura, Park, Eun-Jung, Kondratyuk, Tamara P., Jermihov, Katherine, Mesecar, Andrew D., Pezzuto, John M., Asolkar, Ratnakar N., Fenical, William, Cushman, Mark
Publicado em 2010

Identification, Synthesis, and Biological Evaluation of the Metabolites of 3-Amino-6-(3'-aminopropyl)-5H-indeno[1,2-c]isoquinoline-5,11-(6H)dione (AM6-36), a Promising Rexinoid Lea...

Por Chen, Lian, Conda-Sheridan, Martin, Narasimha Reddy, P. V., Morrell, Andrew, Park, Eun-Jung, Kondratyuk, Tamara P., Pezzuto, John M., van Breemen, Richard B., Cushman, Mark
Publicado em 2012

Erratum to “Synthesis, biological evaluation, and physicochemical property assessment of 4-substituted 2-phenylaminoquinazolines as Mer tyrosine kinase inhibitors” [Bioorg. Med. Chem. 24 (2016) 3083...

Por Wang, Sheng-Biao, Cui, Mu-Tian, Wang, Xiao-Feng, Ohkoshi, Emika, Goto, Masuo, Yang, De-Xuan, Li, Linna, Yuan, Shoujun, Morris-Natschke, Susan L., Lee, Kuo-Hsiung, Xie, Lan
Publicado no Bioorg Med Chem (2017)

Effect of structural modification in the amine portion of substituted aminobutyl-benzamides as ligands for binding σ(1) and σ(2) receptors

Por Fan, Kuo-Hsien, Lever, John R., Lever, Susan Z.
Publicado em 2011

Synthesis and antitumor activity of bis(hydroxymethyl)propionate analogs of pterostilbene in cisplatin-resistant human oral cancer cells

Por Hsieh, Min-Tsang, Huang, Li-Jiau, Wu, Tian-Shung, Lin, Hui-Yi, Morris-Natschke, Susan L., Lee, Kuo-Hsiung, Kuo, Sheng-Chu
Publicado no Bioorg Med Chem (2018)

Antitumor Agents 286. Design, Synthesis and Structure-Activity Relationships of 3′R,4′R-Disubstituted-2′,2′-dimethyldihydropyrano[2,3-f]chromone (DSP) Analogs as Potent Chemosensit...

Por Zhou, Ting, Shi, Qian, Bastow, Kenneth F., Lee, Kuo-Hsiung
Publicado em 2010

A POTENT AND SELECTIVE INHIBITOR TARGETING HUMAN AND MURINE 12/15-LOX

Por Armstrong, Michelle M., Freedman, Cody J., Jung, Joo Eun, Zheng, Yi, Kalyanaraman, Chakrapani, Jacobson, Matthew P., Simeonov, Anton, Maloney, David J., van Leyen, Klaus, Jadhav, Ajit, Holman, Theodore R.
Publicado no Bioorg Med Chem (2016)

Design and Synthesis of 2-(3-Benzo[b]thienyl)-6,7-methylenedioxyquinolin-4-one Analogs as Potent Antitumor Agents that Inhibit Tubulin Assembly

Por Chang, Yu-Hsun, Hsu, Mei-Hua, Wang, Sheng-Hung, Huang, Li-Jiau, Qian, Keduo, Morris-Natschke, Susan L., Hamel, Ernest, Kuo, Sheng-Chu, Lee, Kuo-Hsiung
Publicado em 2009