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1

Computer-aided pulmonary image analysis in small animal models

Computer-aided pulmonary image analysis in small animal models

Por Xu, Ziyue, Bagci, Ulas, Mansoor, Awais, Kramer-Marek, Gabriela, Luna, Brian, Kubler, Andre, Dey, Bappaditya, Foster, Brent, Papadakis, Georgios Z., Camp, Jeremy V., Jonsson, Colleen B., Bishai, William R., Jain, Sanjay, Udupa, Jayaram K., Mollura, Daniel J.
Publicado no Med Phys (2015)

“... EXACT’09 data set. CONCLUSIONS: The authors developed a comprehensive computer-aided pulmonary image...”
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2

Potent New Small-Molecule Inhibitor of Botulinum Neurotoxin Serotype A Endopeptidase Developed by Synthesis-Based Computer-Aided Molecular Design

Potent New Small-Molecule Inhibitor of Botulinum Neurotoxin Serotype A Endopeptidase Developed by Synthesis-Based Computer-Aided Molecular Design

Por Pang, Yuan-Ping, Vummenthala, Anuradha, Mishra, Rajesh K., Park, Jewn Giew, Wang, Shaohua, Davis, Jon, Millard, Charles B., Schmidt, James J.
Publicado em 2009

“... synthesis-based computer-aided molecular design (SBCAMD). This new approach accounts the practicality...”
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3

Electromagnetic tracking for abdominal interventions in computer aided surgery

Electromagnetic tracking for abdominal interventions in computer aided surgery

Por Zhang, Hui, Banovac, Filip, Lin, Ralph, Glossop, Neil, Wood, Bradford J., Lindisch, David, Levy, Elliot, Cleary, Kevin
Publicado em 2006

“.... To fully exploit the potential of this technology, our research group has been developing a computer aided...”
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4

A Computer-Aided Large Scale Pacemaker Surveillance System

A Computer-Aided Large Scale Pacemaker Surveillance System

Por Covvey, H.D., MacGregor, D.C., Noble, E.J., Goldman, B.S., Wigle, E.D.
Publicado em 1980

“...Beginning in 1972 with a small PDP-8 based system, our Pacemaker Center has continued a commitment...”
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5

Associating Drugs, Targets and Clinical Outcomes into an Integrated Network Affords a New Platform for Computer-Aided Drug Repurposing

Associating Drugs, Targets and Clinical Outcomes into an Integrated Network Affords a New Platform for Computer-Aided Drug Repurposing

Por Oprea, Tudor I., Nielsen, Sonny Kim, Ursu, Oleg, Yang, Jeremy J., Taboureau, Olivier, Mathias, Stephen L., Kouskoumvekaki, lrene, Sklar, Larry A., Bologa, Cristian G.
Publicado em 2011

“...Finding new uses for old drugs is a strategy embraced by the pharmaceutical industry...”
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6

Transfer of computer-aided diagnosis of dyspepsia from one geographical area to another.

Transfer of computer-aided diagnosis of dyspepsia from one geographical area to another.

Por Horrocks, J C, Lambert, D E, McAdam, W A, Morgan, A G, Pacsoo, C, Darnborough, A, De Dombal, F T
Publicado em 1976

“... interviewed immediately before endoscopy and the findings analysed by a small desk-top computer-aided system...”
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7

Recoding of the Vesicular Stomatitis Virus L Gene by Computer-Aided Design Provides a Live, Attenuated Vaccine Candidate

Recoding of the Vesicular Stomatitis Virus L Gene by Computer-Aided Design Provides a Live, Attenuated Vaccine Candidate

Por Wang, Bingyin, Yang, Chen, Tekes, Gergely, Mueller, Steffen, Paul, Aniko, Whelan, Sean P. J., Wimmer, Eckard
Publicado no mBio (2015)

“... new road to attain a balance between VSV virulence and immunogenicity, which could serve as an example...”
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8

Machine learning associated with respiratory oscillometry: a computer-aided diagnosis system for the detection of respiratory abnormalities in systemic sclerosis

Machine learning associated with respiratory oscillometry: a computer-aided diagnosis system...

Por Andrade, Domingos S. M., Ribeiro, Luigi Maciel, Lopes, Agnaldo J., Amaral, Jorge L. M., Melo, Pedro L.
Publicado no Biomed Eng Online (2021)

“.... They resulted in a small increase in diagnostic accuracy in CGvsPSNS (respectively, 0.87, 0.86, 0.82, and 0.84...”
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9

Standardized evaluation of algorithms for computer-aided diagnosis of dementia based on structural MRI: the CADDementia challenge

Standardized evaluation of algorithms for computer-aided diagnosis of dementia based on structural MRI: the CADDementia challenge

Por Bron, Esther E., Smits, Marion, van der Flier, Wiesje M., Vrenken, Hugo, Barkhof, Frederik, Scheltens, Philip, Papma, Janne M., Steketee, Rebecca M.E., Orellana, Carolina Méndez, Meijboom, Rozanna, Pinto, Madalena, Meireles, Joana R., Garrett, Carolina, Bastos-Leite, António J., Abdulkadir, Ahmed, Ronneberger, Olaf, Amoroso, Nicola, Bellotti, Roberto, Cárdenas-Peña, David, Álvarez-Meza, Andrés M., Dolph, Chester V., Iftekharuddin, Khan M., Eskildsen, Simon F., Coupé, Pierrick, Fonov, Vladimir S., Franke, Katja, Gaser, Christian, Ledig, Christian, Guerrero, Ricardo, Tong, Tong, Gray, Katherine R., Moradi, Elaheh, Tohka, Jussi, Routier, Alexandre, Durrleman, Stanley, Sarica, Alessia, Di Fatta, Giuseppe, Sensi, Francesco, Chincarini, Andrea, Smith, Garry M., Stoyanov, Zhivko V., Sørensen, Lauge, Nielsen, Mads, Tangaro, Sabina, Inglese, Paolo, Wachinger, Christian, Reuter, Martin, van Swieten, John C., Niessen, Wiro J., Klein, Stefan
Publicado no Neuroimage (2015)

“...Algorithms for computer-aided diagnosis of dementia based on structural MRI have demonstrated high...”
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10

Multivariate Tensor-based Morphometry on Surfaces: Application to Mapping Ventricular Abnormalities in HIV/AIDS

Multivariate Tensor-based Morphometry on Surfaces: Application to Mapping Ventricular Abnormalities in HIV/AIDS

Por Wang, Yalin, Zhang, Jie, Gutman, Boris, Chan, Tony F., Becker, James T., Aizenstein, Howard J., Lopez, Oscar L., Tamburo, Robert J., Toga, Arthur W., Thompson, Paul M.
Publicado em 2009

“...Here we developed a new method, called multivariate tensor-based surface morphometry (TBM...”
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11

Drugsniffer: An Open Source Workflow for Virtually Screening Billions of Molecules for Binding Affinity to Protein Targets

Drugsniffer: An Open Source Workflow for Virtually Screening Billions of Molecules for Binding Affinity to Protein Targets

Por Vishwesh Venkatraman, Thomas H. Colligan, George T. Lesica, Daniel R. Olson, Jeremiah Gaiser, Conner J. Copeland, Travis J. Wheeler, Amitava Roy, Amitava Roy
Publicado em 2022-04-01

Assuntos: “...computer aided drug design...”
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12

How Good is Jarzynski’s Equality for Computer-Aided Drug Design?

How Good is Jarzynski’s Equality for Computer-Aided Drug Design?

Por Ho, Kiet, Truong, Duc Toan, Li, Mai Suan
Publicado no J Phys Chem B (2020)

“... remains a difficult problem in computer-aided drug design. Here, we study and compare the efficiency...”
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13

Computer-aided Detection Fidelity of Pulmonary Nodules in Chest Radiograph

Computer-aided Detection Fidelity of Pulmonary Nodules in Chest Radiograph

Por Dellios, Nikolaos, Teichgraeber, Ulf, Chelaru, Robert, Malich, Ansgar, Papageorgiou, Ismini E
Publicado no J Clin Imaging Sci (2017)

“... of the computer-aided detection (CAD) software package SoftView™ 2.4A for bone suppression and OnGuard™ 5.2...”
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14

Single incision laparoscopic surgery approach for obscure small intestine bleeding localized by CT guided percutaneous injection of methylene blue

Single incision laparoscopic surgery approach for obscure small intestine bleeding localized by CT guided percutaneous injection of methylene blue

Por Martinez, Juan Carlos, Thomas, Jamie L., Lukaszczyk, John J.
Publicado no Int J Surg Case Rep (2014)

“... facilitated more accurate visualization of the small intestine. If a bleeding lesion is identified...”
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15

The Syncardia(™) total artificial heart: in vivo, in vitro, and computational modeling studies

The Syncardia(™) total artificial heart: in vivo, in vitro, and computational modeling studies

Por Slepian, Marvin J., Alemu, Yared, Soares, João Silva, Smith, Richard G., Einav, Shmuel, Bluestein, Danny
Publicado em 2013

“... and overall device thrombogenicity. To aid in the development of a new “pediatric,” TAH an engineering...”
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16

Development of Pharmacophore Models for Small Molecules Targeting RNA: Application to the RNA Repeat Expansion in Myotonic Dystrophy Type 1

Development of Pharmacophore Models for Small Molecules Targeting RNA: Application to the RNA Repeat Expansion in Myotonic Dystrophy Type 1

Por Angelbello, Alicia J., González, Àlex L., Rzuczek, Suzanne G., Disney, Matthew D.
Publicado no Bioorg Med Chem Lett (2016)

“... that bind a specific RNA target with sufficient potency remains a challenge. Computer-aided drug design...”
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17

P finder: genomic and metagenomic annotation of RNase P RNA gene (rnpB)

P finder: genomic and metagenomic annotation of RNase P RNA gene (rnpB)

Por Ellis, J. Christopher
Publicado no BMC Genomics (2020)

“... four new rnpB genes that encode the minimal T-type P RNase P RNAs were identified computationally...”
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18

The small molecule IMR-1 inhibits the Notch transcriptional activation complex to suppress tumorigenesis

The small molecule IMR-1 inhibits the Notch transcriptional activation complex to suppress tumorigenesis

Por Astudillo, Luisana, Da Silva, Thiago G., Wang, Zhiqiang, Han, Xiaoqing, Jin, Ke, VanWye, Jeffrey, Zhu, Xiaoxia, Weaver, Kelly, Oashi, Taiji, Lopes, Pedro E.M., Orton, Darren, Neitzel, Leif R., Lee, Ethan, Landgraf, Ralf, Robbins, David J, MacKerell, Alexander D., Capobianco, Anthony J.
Publicado no Cancer Res (2016)

“... disrupt the assembly of the Notch transcriptional activation complex. We identified a small molecule...”
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19

Morphological analysis and computer-aided, three dimensional reconstruction of chondrocytic columns in rabbit growth plates.

Morphological analysis and computer-aided, three dimensional reconstruction of chondrocytic columns in rabbit growth plates.

Por Moss-Salentijn, L, Moss, M L, Shinozuka, M, Skalak, R
Publicado em 1987

“... their length, while others had duplications. Computer-aided, three dimensional graphic reconstructions were...”
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20

Hotspot Hunter: a computational system for large-scale screening and selection of candidate immunological hotspots in pathogen proteomes

Hotspot Hunter: a computational system for large-scale screening and selection of candidate immunological hotspots in pathogen proteomes

Por Zhang, Guang Lan, Khan, Asif M, Srinivasan, Kellathur N, Heiny, AT, Lee, KX, Kwoh, Chee Keong, August, J Thomas, Brusic, Vladimir
Publicado em 2008

“... at . It is a new generation computational tool aiding in epitope-based vaccine design....”
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