Recoding of the Vesicular Stomatitis Virus L Gene by Computer-Aided Design Provides a Live, Attenuated Vaccine Candidate

Codon pair bias (CPB), which has been observed in all organisms, is a neglected genomic phenomenon that affects gene expression. CPB results from synonymous codons that are paired more or less frequently in ORFeomes regardless of codon bias. The effect of an individual codon pair change is usually s...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:mBio
Hauptverfasser: Wang, Bingyin, Yang, Chen, Tekes, Gergely, Mueller, Steffen, Paul, Aniko, Whelan, Sean P. J., Wimmer, Eckard
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Microbiology 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4453547/
https://ncbi.nlm.nih.gov/pubmed/25827413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00237-15
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge