Recoding of the Vesicular Stomatitis Virus L Gene by Computer-Aided Design Provides a Live, Attenuated Vaccine Candidate

Codon pair bias (CPB), which has been observed in all organisms, is a neglected genomic phenomenon that affects gene expression. CPB results from synonymous codons that are paired more or less frequently in ORFeomes regardless of codon bias. The effect of an individual codon pair change is usually s...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:mBio
Egile Nagusiak: Wang, Bingyin, Yang, Chen, Tekes, Gergely, Mueller, Steffen, Paul, Aniko, Whelan, Sean P. J., Wimmer, Eckard
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Microbiology 2015
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4453547/
https://ncbi.nlm.nih.gov/pubmed/25827413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00237-15
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