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Mechanism of RNA synthesis initiation by the vesicular stomatitis virus polymerase

The minimal RNA synthesis machinery of non-segmented negative-strand RNA viruses comprises a genomic RNA encased within a nucleocapsid protein (N-RNA), and associated with the RNA-dependent RNA polymerase (RdRP). The RdRP is contained within a viral large (L) protein, which associates with N-RNA thr...

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Bibliographic Details
Main Authors: Morin, Benjamin, Rahmeh, Amal A, Whelan, Sean PJ
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3297992/
https://ncbi.nlm.nih.gov/pubmed/22246179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.483
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