Critical phosphoprotein elements that regulate polymerase architecture and function in vesicular stomatitis virus

The RNA-dependent RNA polymerase (RdRP) of nonsegmented negative-sense RNA viruses consists of a large catalytic protein (L) and a phosphoprotein cofactor (P). During infection, the RdRP replicates and transcribes the viral genome, which resides inside an oligomer of nucleocapsid protein (N-RNA). Th...

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Détails bibliographiques
Auteurs principaux: Rahmeh, Amal A., Morin, Benjamin, Schenk, Andreas D., Liang, Bo, Heinrich, Bianca S., Brusic, Vesna, Walz, Thomas, Whelan, Sean P. J.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2012
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437890/
https://ncbi.nlm.nih.gov/pubmed/22908284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1209147109
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