Caricamento...
Development of Pharmacophore Models for Small Molecules Targeting RNA: Application to the RNA Repeat Expansion in Myotonic Dystrophy Type 1
RNA is an important drug target, but current approaches to identify bioactive small molecules have been engineered primarily for protein targets. Moreover, the identification of small molecules that bind a specific RNA target with sufficient potency remains a challenge. Computer-aided drug design (C...
Salvato in:
| Pubblicato in: | Bioorg Med Chem Lett |
|---|---|
| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5286915/ https://ncbi.nlm.nih.gov/pubmed/27839685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2016.10.037 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|