The Drosophila MCPH1-B isoform is a substrate of the APC(Cdh1) E3 ubiquitin ligase complex

Por Hainline, Sarah G., Rickmyre, Jamie L., Neitzel, Leif R., Lee, Laura A., Lee, Ethan
Publicado em 2014

Kabuki syndrome genes KMT2D and KDM6A: functional analyses demonstrate critical roles in craniofacial, heart and brain development

Por Van Laarhoven, Peter M., Neitzel, Leif R., Quintana, Anita M, Geiger, Elizabeth A., Zackai, Elaine H., Clouthier, David E., Artinger, Kristin B., Ming, Jeffrey E., Shaikh, Tamim H.
Publicado no Hum Mol Genet (2015)

The MAPK pathway regulates intrinsic resistance to BET inhibitors in colorectal cancer

Por Ma, Yufang, Wang, Lihong, Neitzel, Leif R., Loganathan, Sudan N., Tang, Nan, Qin, Lili, Crispi, Emily E, Guo, Yan, Knapp, Stefan, Beauchamp, R. Daniel, Lee, Ethan, Wang, Jialiang
Publicado no Clin Cancer Res (2016)

Developmental regulation of Wnt signaling by Nagk and the UDP-GlcNAc salvage pathway

Por Neitzel, Leif R., Spencer, Zachary T., Nayak, Anmada, Cselenyi, Christopher S., Benchabane, Hassina, Youngblood, CheyAnne Q., Zouaoui, Alya, Ng, Victoria, Stephens, Leah, Hann, Trevor, Patton, James G., Robbins, David, Ahmed, Yashi, Lee, Ethan
Publicado no Mech Dev (2019)

Identification of a Paralog-Specific Notch1 Intracellular Domain Degron

Por Broadus, Matthew R., Chen, Tony W., Neitzel, Leif R., Ng, Victoria H., Jodoin, Jeanne N., Lee, Laura A., Salic, Adrian, Robbins, David J., Capobianco, Anthony J., Patton, James G., Huppert, Stacey S., Lee, Ethan
Publicado no Cell Rep (2016)

Phosphorylation of XIAP at threonine 180 controls its activity in Wnt signaling

Por Ng, Victoria H., Hang, Brian I., Sawyer, Leah M., Neitzel, Leif R., Crispi, Emily E., Rose, Kristie L., Popay, Tessa M., Zhong, Alison, Lee, Laura A., Tansey, William P., Huppert, Stacey, Lee, Ethan
Publicado no J Cell Sci (2018)

Comparative genetic screens in human cells reveal new regulatory mechanisms in WNT signaling

Por Lebensohn, Andres M, Dubey, Ramin, Neitzel, Leif R, Tacchelly-Benites, Ofelia, Yang, Eungi, Marceau, Caleb D, Davis, Eric M, Patel, Bhaven B, Bahrami-Nejad, Zahra, Travaglini, Kyle J, Ahmed, Yashi, Lee, Ethan, Carette, Jan E, Rohatgi, Rajat
Publicado no eLife (2016)

Characterization of a cdc14 null allele in Drosophila melanogaster

Por Neitzel, Leif R., Broadus, Matthew R., Zhang, Nailing, Sawyer, Leah, Wallace, Heather A., Merkle, Julie A., Jodoin, Jeanne N., Sitaram, Poojitha, Crispi, Emily E., Rork, William, Lee, Laura A., Pan, Duojia, Gould, Kathleen L., Page-McCaw, Andrea, Lee, Ethan
Publicado no Biol Open (2018)

The small molecule IMR-1 inhibits the Notch transcriptional activation complex to suppress tumorigenesis

Por Astudillo, Luisana, Da Silva, Thiago G., Wang, Zhiqiang, Han, Xiaoqing, Jin, Ke, VanWye, Jeffrey, Zhu, Xiaoxia, Weaver, Kelly, Oashi, Taiji, Lopes, Pedro E.M., Orton, Darren, Neitzel, Leif R., Lee, Ethan, Landgraf, Ralf, Robbins, David J, MacKerell, Alexander D., Capobianco, Anthony J.
Publicado no Cancer Res (2016)

Differential abundance of CK1α provides selectivity for pharmacological CK1α activators to target WNT-dependent tumors

Por Li, Bin, Orton, Darren, Neitzel, Leif R., Astudillo, Luisana, Shen, Chen, Long, Jun, Chen, Xi, Kirkbride, Kellye C., Doundoulakis, Thomas, Guerra, Marcy L., Zaias, Julia, Fei, Dennis Liang, Rodriguez-Blanco, Jezabel, Thorne, Curtis, Wang, Zhiqiang, Jin, Ke, Nguyen, Dao M., Sands, Laurence R., Marchetti, Floriano, Abreu, Maria T., Cobb, Melanie H., Capobianco, Anthony J., Lee, Ethan, Robbins, David J.
Publicado no Sci Signal (2017)

The Role of Bone Morphogenetic Protein Signaling in Non-Alcoholic Fatty Liver Disease

Por Thayer, Timothy E., Lino Cardenas, Christian L., Martyn, Trejeeve, Nicholson, Christopher J., Traeger, Lisa, Wunderer, Florian, Slocum, Charles, Sigurslid, Haakon, Shakartzi, Hannah R., O’Rourke, Caitlin, Shelton, Georgia, Buswell, Mary D., Barnes, Hanna, Neitzel, Leif R., Ledsky, Clara D., Li, Jason Pingcheng, Burke, Megan F., Farber-Eger, Eric, Perrien, Daniel S., Kumar, Ravindra, Corey, Kathleen E., Wells, Quinn S., Bloch, Kenneth D., Hong, Charles C., Bloch, Donald B., Malhotra, Rajeev
Publicado no Sci Rep (2020)