HER2 therapy. HER2 (ERBB2): functional diversity from structurally conserved building blocks

Por Landgraf, Ralf
Publicado em 2007

ERBB3: Multifunctional enabler or primary actor in pancreatic cancer?

Por Landgraf, Ralf
Publicado em 2010

Geldanamycin selectively targets the nascent form of ERBB3 for degradation

Por Gerbin, Candice S., Landgraf, Ralf
Publicado em 2010

Selecting Molecular Recognition. What Can Existing Aptamers Tell Us about Their Inherent Recognition Capabilities and Modes of Interaction?

Por Zhang, Qian, Landgraf, Ralf
Publicado em 2012

Phosphorylated and Unphosphorylated Serine 13 of CDC37 Stabilize Distinct Interactions between Its Client and HSP90 Binding Domains

Por Liu, Wenjun, Landgraf, Ralf
Publicado no Biochemistry (2015)

Higher-Order Association States of Cellular ERBB3 Probed with Photo-Cross-Linkable Aptamers

Por Park, Euisun, Baron, Rose, Landgraf, Ralf
Publicado em 2008

The Growth Factor Receptor ERBB2 Regulates Mitochondrial Activity on a Signaling Time Scale

Por Patel, Nirav, Barrientos, Antoni, Landgraf, Ralf
Publicado em 2013

Functional isolation of activated and unilaterally phosphorylated heterodimers of ERBB2 and ERBB3 as scaffolds in ligand-dependent signaling

Por Zhang, Qian, Park, Euisun, Kani, Kian, Landgraf, Ralf
Publicado em 2012

Binding-induced, turn-on fluorescence of the EGFR/ERBB kinase inhibitor, lapatinib()

Por Wilson, James N., Liu, Wenjun, Brown, Adrienne S., Landgraf, Ralf
Publicado no Org Biomol Chem (2015)

Inhibition of heregulin signaling by an aptamer that preferentially binds to the oligomeric form of human epidermal growth factor receptor-3

Por Chen, Chi-hong B., Chernis, George A., Hoang, Van Q., Landgraf, Ralf
Publicado em 2003

Regulation of Receptor for Advanced Glycation End Products (RAGE) Ectodomain Shedding and Its Role in Cell Function

Por Braley, Alex, Kwak, Taekyoung, Jules, Joel, Harja, Evis, Landgraf, Ralf, Hudson, Barry I.
Publicado no J Biol Chem (2016)

Dynamic Analysis of the Epidermal Growth Factor (EGF) Receptor-ErbB2-ErbB3 Protein Network by Luciferase Fragment Complementation Imaging

Por Macdonald-Obermann, Jennifer L., Adak, Sangeeta, Landgraf, Ralf, Piwnica-Worms, David, Pike, Linda J.
Publicado em 2013

Emission Tuning of Fluorescent Kinase Inhibitors: Conjugation Length and Substituent Effects

Por Dhuguru, Jyothi, Liu, Wenjun, Gonzalez, Walter G., Babinchak, W. Michael, Miksovska, Jaroslava, Landgraf, Ralf, Wilson, James N.
Publicado em 2014

Molecular Mechanism of Protein Kinase Recognition and Sorting by the Hsp90 Kinome-Specific Cochaperone Cdc37

Por Keramisanou, Dimitra, Aboalroub, Adam, Zhang, Ziming, Liu, Wenjun, Marshall, Devon, Diviney, Andrea, Larsen, Randy W., Landgraf, Ralf, Gelis, Ioannis
Publicado no Mol Cell (2016)

HGAL localization to cell membrane regulates B-cell receptor signaling

Por Lu, Xiaoqing, Sicard, Renaud, Jiang, Xiaoyu, Stockus, Jessica N., McNamara, George, Abdulreda, Midhat, Moy, Vincent T., Landgraf, Ralf, Lossos, Izidore S.
Publicado no Blood (2015)

The small molecule IMR-1 inhibits the Notch transcriptional activation complex to suppress tumorigenesis

Por Astudillo, Luisana, Da Silva, Thiago G., Wang, Zhiqiang, Han, Xiaoqing, Jin, Ke, VanWye, Jeffrey, Zhu, Xiaoxia, Weaver, Kelly, Oashi, Taiji, Lopes, Pedro E.M., Orton, Darren, Neitzel, Leif R., Lee, Ethan, Landgraf, Ralf, Robbins, David J, MacKerell, Alexander D., Capobianco, Anthony J.
Publicado no Cancer Res (2016)