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Regulation of Receptor for Advanced Glycation End Products (RAGE) Ectodomain Shedding and Its Role in Cell Function

The receptor for advanced glycation end products (RAGE) is a multiligand transmembrane receptor that can undergo proteolysis at the cell surface to release a soluble ectodomain. Here we observed that ectodomain shedding of RAGE is critical for its role in regulating signaling and cellular function....

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Braley, Alex, Kwak, Taekyoung, Jules, Joel, Harja, Evis, Landgraf, Ralf, Hudson, Barry I.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933258/
https://ncbi.nlm.nih.gov/pubmed/27022018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.702399
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