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Regulation of Receptor for Advanced Glycation End Products (RAGE) Ectodomain Shedding and Its Role in Cell Function

The receptor for advanced glycation end products (RAGE) is a multiligand transmembrane receptor that can undergo proteolysis at the cell surface to release a soluble ectodomain. Here we observed that ectodomain shedding of RAGE is critical for its role in regulating signaling and cellular function....

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Braley, Alex, Kwak, Taekyoung, Jules, Joel, Harja, Evis, Landgraf, Ralf, Hudson, Barry I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933258/
https://ncbi.nlm.nih.gov/pubmed/27022018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.702399
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