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Geldanamycin selectively targets the nascent form of ERBB3 for degradation
Heat shock protein 90 (HSP90) targets a broad spectrum of client proteins with divergent modes of interaction and consequences. The homologous epidermal growth factor receptor (EGFR) and ERBB2 receptors as well as kinase-deficient mutants thereof differ in their requirement for HSP90 in the nascent...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Netherlands
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3006625/ https://ncbi.nlm.nih.gov/pubmed/20084478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-009-0166-1 |
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