Hotspot Hunter: a computational system for large-scale screening and selection of candidate immunological hotspots in pathogen proteomes

BACKGROUND: T-cell epitopes that promiscuously bind to multiple alleles of a human leukocyte antigen (HLA) supertype are prime targets for development of vaccines and immunotherapies because they are relevant to a large proportion of the human population. The presence of clusters of promiscuous T-ce...

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Detalhes bibliográficos
Main Authors: Zhang, Guang Lan, Khan, Asif M, Srinivasan, Kellathur N, Heiny, AT, Lee, KX, Kwoh, Chee Keong, August, J Thomas, Brusic, Vladimir
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Proceedings
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2259420/
https://ncbi.nlm.nih.gov/pubmed/18315850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-S1-S19
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