The Structure-Activity Relationship of Peptide Conjugated Chloramphenicol for Inhibiting E. coli

Por Wang, Jiaqing, Shy, Adrianna, Wu, Difei, Cooper, Deani L., Xu, Jiashu, He, Hongjian, Zhan, Wenjun, Sun, Shenghuan, Lovett, Susan T., Xu, Bing
Publicado no J Med Chem (2019)

Synthesis and Evaluation of Tripodal Peptide Analogues for Cellular Delivery of Phosphopeptides

Por Ye, Guofeng, Nam, Nguyen-Hai, Kumar, Anil, Saleh, Ali, Shenoy, Dinesh B., Amiji, Mansoor M., Lin, Xiaofeng, Sun, Gongqin, Parang, Keykavous
Publicado em 2007

Synthetic resveratrol aliphatic acid inhibits TLR2-mediated apoptosis and an involvement of Akt/GSK3β pathway

Por Chen, Lin, Zhang, Yi, Sun, Xiuli, Li, Hui, LeSage, Gene, Javer, Avani, Zhang, Xiumei, Wei, Xinbing, Jiang, Yulin, Yin, Deling
Publicado em 2009

Degrasyn-like Symmetrical Compounds: Possible Therapeutic Agents for Multiple Myeloma (MM-I)

Por Peng, Zhenghong, Maxwell, David, Sun, Duoli, Bhanu Prasad, Basvoju A., Schuber, Paul T., Pal, Ashutosh, Ying, Yunming, Han, Dongmei, Gao, Liwei, Wang, Shimei, Levitzki, Alexander, Kapuria, Vaibhav, Talpaz, Moshe, Young, Matthew, Showalter, Hollis D., Donato, Nicholas J., Bornmann, William. G.
Publicado em 2014

Design, Synthesis, and Evaluation of Prodrugs of Ertapenem

Por Singh, Sheo B., Rindgen, Diane, Bradley, Prudence, Cama, Lovji, Sun, Wanying, Hafey, Michael J., Suzuki, Takao, Wang, Nengxue, Wu, Hao, Zhang, Basheng, Wang, Li, Ji, Chongmin, Yu, Hongshi, Soll, Richard, Olsen, David B., Meinke, Peter T., Nicoll-Griffith, Deborah A.
Publicado em 2013

Discovery of 5-Phenyl-N-(pyridin-2-ylmethyl)-2-(pyrimidin-5-yl)quinazolin-4-amine as a Potent I(Kur) Inhibitor

Por Finlay, Heather J., Johnson, James A., Lloyd, John L., Jiang, Ji, Neels, James, Gunaga, Prashantha, Banerjee, Abhisek, Dhondi, Naveen, Chimalakonda, Anjaneya, Mandlekar, Sandhya, Conder, Mary Lee, Sale, Harinath, Xing, Dezhi, Levesque, Paul, Wexler, Ruth R.
Publicado no ACS Med Chem Lett (2016)

Small molecule KDM4s inhibitors as anti-cancer agents

Por Lin, Hongzhi, Li, Qihang, Li, Qi, Zhu, Jie, Gu, Kai, Jiang, Xueyang, Hu, Qianqian, Feng, Feng, Qu, Wei, Chen, Yao, Sun, Haopeng
Publicado no J Enzyme Inhib Med Chem (2018)

Identification of myricetin and scutellarein as novel chemical inhibitors of the SARS coronavirus helicase, nsP13

Por Yu, Mi-Sun, Lee, June, Lee, Jin Moo, Kim, Younggyu, Chin, Young-Won, Jee, Jun-Goo, Keum, Young-Sam, Jeong, Yong-Joo
Publicado no Bioorg Med Chem Lett (2012)

Sulfamoylbenzamide-based Capsid Assembly Modulators for Selective Inhibition of Hepatitis B Viral Replication

Por Lee, Yeon Hee, Cha, Hyeon-Min, Hwang, Jun Yeon, Park, So Yeong, Vishakantegowda, Avinash G., Imran, Ali, Lee, Joo-Youn, Yi, Yoon-Sun, Jun, Sangmi, Kim, Ga Hyeon, Kang, Hyo Jin, Chung, Sang J., Kim, Meehyein, Kim, Hyejin, Han, Soo Bong
Publicado no ACS Med Chem Lett (2021)

Structure–Activity Relationship in a Purine-Scaffold Compound Series with Selectivity for the Endoplasmic Reticulum Hsp90 Paralog Grp94

Por Patel, Hardik J., Patel, Pallav D., Ochiana, Stefan O., Yan, Pengrong, Sun, Weilin, Patel, Maulik R., Shah, Smit K., Tramentozzi, Elisa, Brooks, James, Bolaender, Alexander, Shrestha, Liza, Stephani, Ralph, Finotti, Paola, Leifer, Cynthia, Li, Zihai, Gewirth, Daniel T., Taldone, Tony, Chiosis, Gabriela
Publicado no J Med Chem (2015)

Development of 2,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one inhibitors of Aldehyde Dehydrogenase 1A (ALDH1A) as potential adjuncts to ovarian cancer chemotherapy

Por Huddle, Brandt C., Grimley, Edward, Chtcherbinine, Mikhail, Buchman, Cameron D., Takahashi, Cyrus, Debnath, Bikash, McGonigal, Stacy C., Mao, Shuai, Li, Siwei, Felton, Jeremy, Pan, Shu, Wen, Bo, Sun, Duxin, Neamati, Nouri, Buckanovich, Ronald J., Hurley, Thomas D., Larsen, Scott D.
Publicado no Eur J Med Chem (2020)

D-isoascorbyl palmitate: lipase-catalyzed synthesis, structural characterization and process optimization using response surface methodology

Por Sun, Wen-Jing, Zhao, Hong-Xia, Cui, Feng-Jie, Li, Yun-Hong, Yu, Si-Lian, Zhou, Qiang, Qian, Jing-Ya, Dong, Ying
Publicado em 2013

Fragment-based cocktail crystallography by the Medical Structural Genomics of Pathogenic Protozoa Consortium

Por Verlinde, Christophe L.M.J., Fan, Erkang, Shibata, Sayaka, Zhang, Zongsheng, Sun, Zhihua, Deng, Wei, Ross, Jennifer, Kim, Jessica, Xiao, Liren, Arakaki, Tracy L., Bosch, Jürgen, Caruthers, Jonathan M., Larson, Eric T., LeTrong, Isolde, Napuli, Alberto, Kelly, Angela, Mueller, Natasha, Zucker, Frank, Van Voorhis, Wesley C., Buckner, Frederick S., Merritt, Ethan A., Hol, Wim G.J.
Publicado em 2009

Assessing the Perturbing Effects of Drugs on Lipid Bilayers Using Gramicidin Channel-Based In Silico and In Vitro Assays

Por Sun, Delin, Peyear, Thasin A., Bennett, W. F. Drew, Holcomb, Matthew, He, Stewart, Zhu, Fangqiang, Lightstone, Felice C., Andersen, Olaf S., Ingólfsson, Helgi I.
Publicado no J Med Chem (2020)

Synthesis, modification and docking studies of 5-sulfonyl isatin derivatives as SARS-CoV 3C-like protease inhibitors

Por Liu, Wei, Zhu, He-Min, Niu, Guo-Jun, Shi, En-Zhi, Chen, Jie, Sun, Bo, Chen, Wei-Qiang, Zhou, Hong-Gang, Yang, Cheng
Publicado no Bioorg Med Chem (2014)

Site-Specific Photo-Crosslinking Proteomics Reveal Regulation of IFITM3 Trafficking and Turnover by VCP/p97 ATPase

Por Wu, Xiaojun, Spence, Jennifer S., Das, Tandrila, Yuan, Xiaoqiu, Chen, Chengjie, Zhang, Yuqing, Li, Yumeng, Sun, Yanan, Chandran, Kartik, Hang, Howard C., Peng, Tao
Publicado no Cell Chem Biol (2020)

Discovery of AM-1638: A Potent and Orally Bioavailable GPR40/FFA1 Full Agonist

Por Brown, Sean P., Dransfield, Paul J., Vimolratana, Marc, Jiao, XianYun, Zhu, Liusheng, Pattaropong, Vatee, Sun, Ying, Liu, Jinqian, Luo, Jian, Zhang, Jane, Wong, Simon, Zhuang, Run, Guo, Qi, Li, Frank, Medina, Julio C., Swaminath, Gayathri, Lin, Daniel C.-H., Houze, Jonathan B.
Publicado em 2012

Potent, Orally Bioavailable Diazabicyclic Small-Molecule Mimetics of Second Mitochondria-derived Activator of Caspases

Por Peng, Yuefeng, Sun, Haiying, Nikolovska-Coleska, Zaneta, Qiu, Su, Yang, Chao-Yie, Lu, Jianfeng, Cai, Qian, Yi, Han, Kang, Sanmao, Yang, Dajun, Wang, Shaomeng
Publicado em 2008

Chitin Nanofiber Micropatterned Flexible Substrates for Tissue Engineering(†)

Por Hassanzadeh, Pegah, Kharaziha, Mahshid, Nikkhah, Mehdi, Shin, Su-Ryon, Jin, Jungho, He, Simeiqi, Sun, Wei, Zhong, Chao, Dokmeci, Mehmet R., Khademhosseini, Ali, Rolandi, Marco
Publicado em 2013

Discovery of 5-((5-chloro-2-methoxyphenyl)sulfonamido)nicotinamide (SBI-425), a potent and orally bioavailable tissue-nonspecific alkaline phosphatase (TNAP) inhibitor

Por Pinkerton, Anthony B., Sergienko, Eduard, Bravo, Yalda, Dahl, Russell, Ma, Chen-Ting, Sun, Qing, Jackson, Michael R., Cosford, Nicholas D. P., Millán, José Luis
Publicado no Bioorg Med Chem Lett (2017)