Small molecule KDM4s inhibitors as anti-cancer agents

Histone demethylation is a vital process in epigenetic regulation of gene expression. A number of histone demethylases are present to control the methylated states of histone. Among these enzymes, KDM4s are one subfamily of JmjC KDMs and play important roles in both normal and cancer cells. The disc...

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Vydáno v:J Enzyme Inhib Med Chem
Hlavní autoři: Lin, Hongzhi, Li, Qihang, Li, Qi, Zhu, Jie, Gu, Kai, Jiang, Xueyang, Hu, Qianqian, Feng, Feng, Qu, Wei, Chen, Yao, Sun, Haopeng
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2018
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Review Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010108/
https://ncbi.nlm.nih.gov/pubmed/29651880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2018.1455676
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