Small molecule KDM4s inhibitors as anti-cancer agents

Histone demethylation is a vital process in epigenetic regulation of gene expression. A number of histone demethylases are present to control the methylated states of histone. Among these enzymes, KDM4s are one subfamily of JmjC KDMs and play important roles in both normal and cancer cells. The disc...

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Veröffentlicht in:J Enzyme Inhib Med Chem
Hauptverfasser: Lin, Hongzhi, Li, Qihang, Li, Qi, Zhu, Jie, Gu, Kai, Jiang, Xueyang, Hu, Qianqian, Feng, Feng, Qu, Wei, Chen, Yao, Sun, Haopeng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2018
Schlagworte:
Review Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010108/
https://ncbi.nlm.nih.gov/pubmed/29651880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2018.1455676
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