Small molecule KDM4s inhibitors as anti-cancer agents

Histone demethylation is a vital process in epigenetic regulation of gene expression. A number of histone demethylases are present to control the methylated states of histone. Among these enzymes, KDM4s are one subfamily of JmjC KDMs and play important roles in both normal and cancer cells. The disc...

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Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: Lin, Hongzhi, Li, Qihang, Li, Qi, Zhu, Jie, Gu, Kai, Jiang, Xueyang, Hu, Qianqian, Feng, Feng, Qu, Wei, Chen, Yao, Sun, Haopeng
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Review Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010108/
https://ncbi.nlm.nih.gov/pubmed/29651880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2018.1455676
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