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Synthesis and Evaluation of Tripodal Peptide Analogues for Cellular Delivery of Phosphopeptides

Tripodal peptide analogues were designed based on the phosphotyrosine binding pocket of the Src SH2 domain and assayed for their ability to bind to fluorescein-labeled phosphopeptides. Fluorescence polarization assays showed that a number of amphipathic linear peptide analogues (LPAs), such as LPA4,...

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Detalhes bibliográficos
Main Authors: Ye, Guofeng, Nam, Nguyen-Hai, Kumar, Anil, Saleh, Ali, Shenoy, Dinesh B., Amiji, Mansoor M., Lin, Xiaofeng, Sun, Gongqin, Parang, Keykavous
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2539070/
https://ncbi.nlm.nih.gov/pubmed/17580848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm070416o
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