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Synthesis and Evaluation of Phosphopeptides Containing Iminodiacetate Groups as Binding Ligands of the Src SH2 Domain

Phosphopeptide pTyr-Glu-Glu-Ile (pYEEI) has been introduced as an optimal Src SH2 domain ligand. Peptides, Ac-K(IDA)pYEEIEK(IDA) (1), Ac-KpYEEIEK (2), Ac-K(IDA)pYEEIEK (3), and Ac-KpYEEIEK(IDA) (4), containing 0–2 iminodiacetate (IDA) groups at the N- and C-terminal lysine residues were synthesized...

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Dettagli Bibliografici
Autori principali: Ye, Guofeng, Schuler, Aaron D., Ahmadibeni, Yousef, Morgan, Joel R., Faruqui, Absar, Huang, Kezhen, Sun, Gongqin, Zebala, John A., Parang, Keykavous
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754053/
https://ncbi.nlm.nih.gov/pubmed/19539345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bioorg.2009.05.003
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