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Synthesis of Nucleoside Mono-, Di-, and Triphosphoramidates from Solid-Phase CycloSaligenyl Phosphitylating Reagents
[Image: see text] Chloromethyl polystyrene resin was reacted with 5-hydroxysalicylaldehyde in the presence of potassium carbonate to afford polymer-bound 2-hydroxybenzaldehyde. Subsequent reduction with borane solution produced polymer-bound 2-hydroxybenzyl alcohol. The reaction of immobilized 2-hyd...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2688834/ https://ncbi.nlm.nih.gov/pubmed/19364114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol900320r |
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