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Inhibition of multi-drug resistant HIV-1 reverse transcriptase by nucleoside β-triphosphates
Despite the success of potent reverse transcriptase (RT) inhibitors against human immunodeficiency virus type 1 (HIV-1) in combination regimens, the development of drug resistant RTs constitutes a major hurdle for the long-term efficacy of current antiretroviral therapy. Nucleoside β-triphosphate an...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3114884/ https://ncbi.nlm.nih.gov/pubmed/21605974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.05.005 |
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