Identification of Potential Small Molecule Allosteric Modulator Sites on IL-1R1 Ectodomain Using Accelerated Conformational Sampling Method

od Yang, Chao-Yie
Izdano u PLoS One (2015)

Comparative Analyses of the Conformational Dynamics Between the Soluble and Membrane-Bound Cytokine Receptors

od Yang, Chao-Yie
Izdano u Sci Rep (2020)

Computational Analysis of Protein Hotspots

od Yang, Chao-Yie, Wang, Shaomeng
Izdano 2010

Analysis of Flexibility and Hotspots in Bcl-xL and Mcl-1 Proteins for the Design of Selective Small-Molecule Inhibitors

od Yang, Chao-Yie, Wang, Shaomeng
Izdano 2012

Hydrophobic Binding Hot Spots of Bcl-xL Protein−Protein Interfaces by Cosolvent Molecular Dynamics Simulation

od Yang, Chao-Yie, Wang, Shaomeng
Izdano 2011

MCL-1 inhibition in cancer treatment

od Xiang, Weiguo, Yang, Chao-Yie, Bai, Longchuan
Izdano u Onco Targets Ther (2018)

Enrichment of Druggable Conformations from Apo Protein Structures Using Cosolvent-Accelerated Molecular Dynamics

od Kalenkiewicz, Andrew, Grant, Barry J., Yang, Chao-Yie
Izdano u Biology (Basel) (2015)

Targeting Inhibitors of Apoptosis Proteins (IAPs) For New Breast Cancer Therapeutics

od Wang, Shaomeng, Bai, Longchuan, Lu, Jianfeng, Liu, Liu, Yang, Chao-Yie
Izdano 2012

Potent and Selective Small-Molecule Inhibitors of cIAP1/2 Proteins Reveal That the Binding of Smac Mimetics to XIAP BIR3 Is Not Required for Their Effective Induction of Cell Death...

od Sun, Haiying, Lu, Jianfeng, Liu, Liu, Yang, Chao-Yie, Wang, Shaomeng
Izdano u ACS Chem Biol (2014)

Targeting the MDM2–p53 Protein–Protein Interaction for New Cancer Therapy: Progress and Challenges

od Wang, Shaomeng, Zhao, Yujun, Aguilar, Angelo, Bernard, Denzil, Yang, Chao-Yie
Izdano u Cold Spring Harb Perspect Med (2017)

Importance of Ligand Reorganization Free Energy in Protein-Ligand Binding-Affinity Prediction

od Yang, Chao-Yie, Sun, Haiying, Chen, Jianyong, Nikolovska-Coleska, Zaneta, Wang, Shaomeng
Izdano 2009

The FHA and BRCT domains recognize ADP-ribosylation during DNA damage response

od Li, Mo, Lu, Lin-Yu, Yang, Chao-Yie, Wang, Shaomeng, Yu, Xiaochun
Izdano 2013

RNF111-dependent neddylation activates DNA damage-induced ubiquitination

od Ma, Teng, Chen, Yibin, Zhang, Feng, Yang, Chao-Yie, Wang, Shaomeng, Yu, Xiaochun
Izdano 2013

Simple Structural Modifications Converting a Bona Fide MDM2 PROTAC Degrader into a Molecular Glue Molecule: A Cautionary Tale in the Design of PROTAC Degraders

od Yang, Jiuling, Li, Yangbing, Aguilar, Angelo, Liu, Zhaomin, Yang, Chao-Yie, Wang, Shaomeng
Izdano u J Med Chem (2019)

Design of Triazole-stapled BCL9 α-Helical Peptides to Target the β-Catenin/B-cell CLL/lymphoma 9 (BCL9) Protein-Protein Interaction

od Kawamoto, Steven A., Coleska, Adriana, Ran, Xu, Yi, Han, Yang, Chao-Yie, Wang, Shaomeng
Izdano 2012

LRIG1 modulates cancer cell sensitivity to Smac mimetics by regulating TNFα expression and receptor tyrosine kinase signaling

od Bai, Longchuan, McEachern, Donna, Yang, Chao-Yie, Lu, Jianfeng, Sun, Haiying, Wang, Shaomeng
Izdano 2012

Design, Synthesis and Evaluation of Potent and Selective Ligands for the Dopamine 3 (D(3)) Receptor with a Novel in vivo Behavioral Profile

od Chen, Jianyong, Collins, Gregory T., Zhang, Jian, Yang, Chao-Yie, Levant, Beth, Woods, James, Wang, Shaomeng
Izdano 2008

Cyclopeptide Smac mimetics as antagonists of IAP proteins

od Sun, Haiying, Liu, Liu, Lu, Jianfeng, Qiu, Su, Yang, Chao-Yie, Yi, Han, Wang, Shaomeng
Izdano 2010

Conformational Sampling and Binding Site Assessment of Suppression of Tumorigenicity 2 Ectodomain

od Yang, Chao-Yie, Delproposto, James, Chinnaswamy, Krishnapriya, Brown, William Clay, Wang, Shuying, Stuckey, Jeanne A., Wang, Xinquan
Izdano u PLoS One (2016)

Non-peptidic and Potent Small-Molecule Inhibitors of cIAP-1/2 and XIAP Proteins

od Sun, Haiying, Lu, Jianfeng, Liu, Liu, Yi, Han, Qiu, Su, Yang, Chao-Yie, Deschamps, Jeffrey R., Wang, Shaomeng
Izdano 2010