Four-Dimensional Visualization of the Simultaneous Activity of Alternative Adeno-Associated Virus Replication Origins

The adeno-associated virus (AAV) inverted terminal repeats (ITRs) contain the AAV Rep protein-binding site (RBS) and the terminal resolution site (TRS), which together act as a minimal origin of DNA replication. The AAV p5 promoter also contains an RBS, which is involved in Rep-mediated regulation o...

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Bibliographic Details
Main Authors: Glauser, Daniel L., Saydam, Okay, Balsiger, N. Alexander, Heid, Irma, Linden, R. Michael, Ackermann, Mathias, Fraefel, Cornel
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1211535/
https://ncbi.nlm.nih.gov/pubmed/16160148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.19.12218-12230.2005
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