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Adeno-Associated Virus Type 5 Utilizes Alternative Translation Initiation To Encode a Small Rep40-Like Protein

Alternative splicing of adeno-associated virus type 2 (AAV2) P19-generated pre-mRNAs generates the small Rep proteins Rep52 and Rep40, which differ in their carboxyl termini. Both proteins are required for optimal packaging of AAV2 genomes. AAV5 Rep-encoding P19-generated transcripts are primarily p...

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Bibliografische gegevens
Hoofdauteurs: Farris, K. David, Pintel, David J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798364/
https://ncbi.nlm.nih.gov/pubmed/19889770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01961-09
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