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The Adeno-Associated Virus Type 5 Small Rep Proteins Expressed via Internal Translation Initiation Are Functional

Although precluded from using splicing to produce multiple small Rep proteins, adeno-associated virus type 5 (AAV5) generates a Rep40-like protein by alternative translation initiation at an internal AUG. A defined region upstream of the internal AUG was both required and sufficient to program inter...

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Main Authors: Fasina, Olufemi, Pintel, David J.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536406/
https://ncbi.nlm.nih.gov/pubmed/23077303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02547-12
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