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cis Effects in Adeno-Associated Virus Type 2 Replication

We have utilized deletion mutants of adeno-associated virus (AAV) to investigate which elements of the AAV genome are required in cis for high yields of the wild-type virus in a plasmid transfection assay and in addition whether these elements affect primarily AAV DNA replication or encapsidation. A...

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Detalhes bibliográficos
Main Authors: Ward, Peter, Clément, Nathalie, Linden, R. Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045438/
https://ncbi.nlm.nih.gov/pubmed/17626079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00630-07
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