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Differential Contribution of Adeno-Associated Virus Type 2 Rep Protein Expression and Nucleic Acid Elements to Inhibition of Adenoviral Replication in cis and in trans

The helper-dependent adeno-associated virus type 2 (AAV-2) exhibits complex interactions with its helper adenovirus. Whereas AAV-2 is dependent on adenoviral functions for productive replication, it conversely inhibits adenoviral replication, both when its genome is present in trans after coinfectio...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Weger, Stefan, Hammer, Eva, Heilbronn, Regine
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249140/
https://ncbi.nlm.nih.gov/pubmed/25275117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02350-14
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