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Cell Cycle-Dependent Expression of Adeno-Associated Virus 2 (AAV2) Rep in Coinfections with Herpes Simplex Virus 1 (HSV-1) Gives Rise to a Mosaic of Cells Replicating either AAV2 or HSV-1
Adeno-associated virus 2 (AAV2) depends on the simultaneous presence of a helper virus such as herpes simplex virus 1 (HSV-1) for productive replication. At the same time, AAV2 efficiently blocks the replication of HSV-1, which would eventually limit its own replication by diminishing the helper vir...
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Published in: | J Virol |
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Main Authors: | , , , , , , , , , , , , |
Format: | Artigo |
Language: | Inglês |
Published: |
American Society for Microbiology
2017
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5512256/ https://ncbi.nlm.nih.gov/pubmed/28515305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00357-17 |
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