Herpes Simplex Virus Type 1/Adeno-Associated Virus Hybrid Vectors Mediate Site-Specific Integration at the Adeno-Associated Virus Preintegration Site, AAVS1, on Human Chromosome 19

Herpes simplex virus type 1 (HSV-1)-based amplicon vectors have a large transgene capacity and can efficiently infect many different cell types. One disadvantage of HSV-1 vectors is their instability of transgene expression. By contrast, vectors based on adeno-associated virus (AAV) can either persi...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Heister, Thomas, Heid, Irma, Ackermann, Mathias, Fraefel, Cornel
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Gene Therapy
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136299/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12072516/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.14.7163-7173.2002
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