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Herpes simplex virus co-infection facilitates rolling circle replication of the adeno-associated virus genome.

Adeno-associated virus (AAV) genome replication only occurs in the presence of a co-infecting helper virus such as adenovirus type 5 (AdV5) or herpes simplex virus type 1 (HSV-1). AdV5-supported replication of the AAV genome has been described to occur in a strand-displacement rolling hairpin replic...

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Principais autores: Anita Felicitas Meier, Kurt Tobler, Remo Leisi, Anouk Lkharrazi, Carlos Ros, Cornel Fraefel
格式: Artigo
語言:Inglês
出版: Public Library of Science (PLoS) 2021-06-01
叢編:PLoS Pathogens
在線閱讀:https://doi.org/10.1371/journal.ppat.1009638
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