Helper virus-free transfer of herpes simplex virus type 1 plasmid vectors into neural cells.

Herpes simplex virus type 1 (HSV-1) plasmid vectors have promise for genetic intervention in the brain, but several problems caused by the helper virus have compromised their utility. To develop a helper virus-free packaging system for these vectors, the DNA cleavage/packaging signals were deleted f...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Fraefel, C, Song, S, Lim, F, Lang, P, Yu, L, Wang, Y, Wild, P, Geller, A I
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190772/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8794366/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.10.7190-7197.1996
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