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Helper virus-free transfer of herpes simplex virus type 1 plasmid vectors into neural cells.

Herpes simplex virus type 1 (HSV-1) plasmid vectors have promise for genetic intervention in the brain, but several problems caused by the helper virus have compromised their utility. To develop a helper virus-free packaging system for these vectors, the DNA cleavage/packaging signals were deleted f...

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Detalhes bibliográficos
Main Authors: Fraefel, C, Song, S, Lim, F, Lang, P, Yu, L, Wang, Y, Wild, P, Geller, A I
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC190772/
https://ncbi.nlm.nih.gov/pubmed/8794366
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