Gene therapy enters the pharma market: The short story of a long journey

Por Büning, Hildegard
Publicado em 2013

Adeno-Associated Viral Vectors at the Frontier between Tolerance and Immunity

Por Mingozzi, Federico, Büning, Hildegard
Publicado no Front Immunol (2015)

Adeno-associated Vector Toxicity—To Be or Not to Be?

Por Büning, Hildegard, Schmidt, Manfred
Publicado no Mol Ther (2015)

Enhancing the Clinical Potential of AAV Vectors by Capsid Engineering to Evade Pre-Existing Immunity

Por Bartel, Melissa, Schaffer, David, Büning, Hildegard
Publicado em 2011

Reply to “Wild-type AAV Insertions in Hepatocellular Carcinoma Do Not Inform Debate Over Genotoxicity Risk of Vectorized AAV”

Por Schmidt, Manfred, Gil-Farina, Irene, Büning, Hildegard
Publicado no Mol Ther (2016)

Adeno-Associated Virus Capsids Displaying Immunoglobulin-Binding Domains Permit Antibody-Mediated Vector Retargeting to Specific Cell Surface Receptors

Por Ried, Martin U., Girod, Anne, Leike, Kristin, Büning, Hildegard, Hallek, Michael
Publicado em 2002

Gene therapy on the move

Por Kaufmann, Kerstin B, Büning, Hildegard, Galy, Anne, Schambach, Axel, Grez, Manuel
Publicado em 2013

Incorporation of Antigens into Viral Capsids Augments Immunogenicity of Adeno-Associated Virus Vector-Based Vaccines

Por Rybniker, Jan, Nowag, Angela, Janicki, Hanna, Demant, Kai, Hartmann, Pia, Büning, Hildegard
Publicado em 2012

In vivo imaging reveals a phase-specific role of STAT3 during central and peripheral nervous system axon regeneration

Por Bareyre, Florence M., Garzorz, Natalie, Lang, Claudia, Misgeld, Thomas, Büning, Hildegard, Kerschensteiner, Martin
Publicado em 2011

Displaying High-affinity Ligands on Adeno-associated Viral Vectors Enables Tumor Cell-specific and Safe Gene Transfer

Por Münch, Robert C, Janicki, Hanna, Völker, Iris, Rasbach, Anke, Hallek, Michael, Büning, Hildegard, Buchholz, Christian J
Publicado em 2013

A Role for the Human Nucleotide-binding Domain, Leucine-rich Repeat-containing Family Member NLRC5 in Antiviral Responses

Por Neerincx, Andreas, Lautz, Katja, Menning, Maureen, Kremmer, Elisabeth, Zigrino, Paola, Hösel, Marianna, Büning, Hildegard, Schwarzenbacher, Robert, Kufer, Thomas A.
Publicado em 2010

Impact of the MRN Complex on Adeno-Associated Virus Integration and Replication during Coinfection with Herpes Simplex Virus 1

Por Millet, Rachel, Jolinon, Nelly, Nguyen, Xuan-Nhi, Berger, Gregory, Cimarelli, Andrea, Greco, Anna, Bertrand, Pascale, Odenthal, Margarete, Büning, Hildegard, Salvetti, Anna
Publicado no J Virol (2015)

Gene Editing for the Efficient Correction of a Recurrent COL7A1 Mutation in Recessive Dystrophic Epidermolysis Bullosa Keratinocytes

Por Chamorro, Cristina, Mencía, Angeles, Almarza, David, Duarte, Blanca, Büning, Hildegard, Sallach, Jessica, Hausser, Ingrid, Del Río, Marcela, Larcher, Fernando, Murillas, Rodolfo
Publicado no Mol Ther Nucleic Acids (2016)

DNA Minicircle Technology Improves Purity of Adeno-associated Viral Vector Preparations

Por Schnödt, Maria, Schmeer, Marco, Kracher, Barbara, Krüsemann, Christa, Espinosa, Laura Escalona, Grünert, Anja, Fuchsluger, Thomas, Rischmüller, Anja, Schleef, Martin, Büning, Hildegard
Publicado no Mol Ther Nucleic Acids (2016)

Green Fluorescent Protein-Tagged Adeno-Associated Virus Particles Allow the Study of Cytosolic and Nuclear Trafficking

Por Lux, Kerstin, Goerlitz, Nico, Schlemminger, Stefanie, Perabo, Luca, Goldnau, Daniela, Endell, Jan, Leike, Kristin, Kofler, David M., Finke, Stefan, Hallek, Michael, Büning, Hildegard
Publicado em 2005

Adeno-Associated Virus Type 2 Rep68 Can Bind to Consensus Rep-Binding Sites on the Herpes Simplex Virus 1 Genome

Por Seyffert, Michael, Glauser, Daniel L., Tobler, Kurt, Georgiev, Oleg, Vogel, Rebecca, Vogt, Bernd, Agúndez, Leticia, Linden, Michael, Büning, Hildegard, Ackermann, Mathias, Fraefel, Cornel
Publicado no J Virol (2015)

Evaluation of Angiopoietin-2 as a biomarker in gastric cancer: results from the randomised phase III AVAGAST trial

Por Hacker, Ulrich T, Escalona-Espinosa, Laura, Consalvo, Nicola, Goede, Valentin, Schiffmann, Lars, Scherer, Stefan J, Hedge, Priti, Van Cutsem, Eric, Coutelle, Oliver, Büning, Hildegard
Publicado no Br J Cancer (2016)

Heparan Sulfate Proteoglycan Binding Properties of Adeno-Associated Virus Retargeting Mutants and Consequences for Their In Vivo Tropism

Por Perabo, Luca, Goldnau, Daniela, White, Kathryn, Endell, Jan, Boucas, Jorge, Humme, Sibille, Work, Lorraine M., Janicki, Hanna, Hallek, Michael, Baker, Andrew H., Büning, Hildegard
Publicado em 2006

Combined Paracrine and Endocrine AAV9 mediated Expression of Hepatocyte Growth Factor for the Treatment of Renal Fibrosis

Por Schievenbusch, Stephanie, Strack, Ingo, Scheffler, Melanie, Nischt, Roswitha, Coutelle, Oliver, Hösel, Marianna, Hallek, Michael, Fries, Jochen WU, Dienes, Hans-Peter, Odenthal, Margarete, Büning, Hildegard
Publicado em 2010

Novel Mutant AAV2 Rep Proteins Support AAV2 Replication without Blocking HSV-1 Helpervirus Replication

Por Seyffert, Michael, Glauser, Daniel L., Schraner, Elisabeth M., de Oliveira, Anna-Paula, Mansilla-Soto, Jorge, Vogt, Bernd, Büning, Hildegard, Linden, R. Michael, Ackermann, Mathias, Fraefel, Cornel
Publicado no PLoS One (2017)