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Analyzing the Genotoxicity of Retroviral Vectors in Hematopoietic Cell Gene Therapy

Retroviral vectors, including those derived from gammaretroviruses and lentiviruses, have found their way into the clinical arena and demonstrated remarkable efficacy for the treatment of immunodeficiencies, leukodystrophies, and globinopathies. Despite these successes, gene therapy unfortunately al...

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Detaylı Bibliyografya
Yayımlandı:Mol Ther Methods Clin Dev
Asıl Yazarlar: Biasco, Luca, Rothe, Michael, Büning, Hildegard, Schambach, Axel
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Gene & Cell Therapy 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5684499/
https://ncbi.nlm.nih.gov/pubmed/29159200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2017.10.002
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