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Retroviral vector interactions with hematopoietic cells

Hematopoietic stem cell (HSC) gene therapy using retroviral vectors has immense potential. Increasing the transduction of quiescent HSCs and reducing genotoxicity are major challenges in the field. Retroviral vectors, including lentiviral and foamy vectors, have been extensively modified resulting i...

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Bibliographic Details
Published in:Curr Opin Virol
Main Authors: Everson, Elizabeth M., Trobridge, Grant D.
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5138074/
https://ncbi.nlm.nih.gov/pubmed/27521874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coviro.2016.07.010
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