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Insulators to Improve the Safety of Retroviral Vectors for HIV Gene Therapy
Retroviral vector gene therapy is a promising approach to treating HIV-1. However, integrated vectors are mutagens with the potential to dysregulate nearby genes and cause severe adverse side effects. Leukemia has already been a documented severe adverse event in gene therapy clinical trials for the...
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| Publicado no: | Biomedicines |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5344246/ https://ncbi.nlm.nih.gov/pubmed/28424756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines4010004 |
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