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Evidence for the in vivo safety of insulated foamy viral vectors
Retroviral vector mediated stem cell gene therapy is a promising approach for the treatment of hematopoietic disorders. However, genotoxic side effects from integrated vector proviruses are a significant concern for the use of retroviral vectors in the clinic. Insulated foamy viral (FV) vectors are...
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Publicado no: | Gene Ther |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5374020/ https://ncbi.nlm.nih.gov/pubmed/28024082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2016.88 |
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