Insulated Foamy Viral Vectors

Retroviral vector-mediated gene therapy is promising, but genotoxicity has limited its use in the clinic. Genotoxicity is highly dependent on the retroviral vector used, and foamy viral (FV) vectors appear relatively safe. However, internal promoters may still potentially activate nearby genes. We d...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Hum Gene Ther
Main Authors: Browning, Diana L., Collins, Casey P., Hocum, Jonah D., Leap, David J., Rae, Dustin T., Trobridge, Grant D.
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc. 2016
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4800274/
https://ncbi.nlm.nih.gov/pubmed/26715244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2015.110
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