Insulated Foamy Viral Vectors

Retroviral vector-mediated gene therapy is promising, but genotoxicity has limited its use in the clinic. Genotoxicity is highly dependent on the retroviral vector used, and foamy viral (FV) vectors appear relatively safe. However, internal promoters may still potentially activate nearby genes. We d...

Full description

Saved in:
Bibliographic Details
Published in:Hum Gene Ther
Main Authors: Browning, Diana L., Collins, Casey P., Hocum, Jonah D., Leap, David J., Rae, Dustin T., Trobridge, Grant D.
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2016
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4800274/
https://ncbi.nlm.nih.gov/pubmed/26715244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2015.110
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items