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Insulated Foamy Viral Vectors

Retroviral vector-mediated gene therapy is promising, but genotoxicity has limited its use in the clinic. Genotoxicity is highly dependent on the retroviral vector used, and foamy viral (FV) vectors appear relatively safe. However, internal promoters may still potentially activate nearby genes. We d...

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Detalhes bibliográficos
Publicado no:Hum Gene Ther
Main Authors: Browning, Diana L., Collins, Casey P., Hocum, Jonah D., Leap, David J., Rae, Dustin T., Trobridge, Grant D.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4800274/
https://ncbi.nlm.nih.gov/pubmed/26715244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2015.110
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