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Foamy viral vector integration sites in SCID-repopulating cells after MGMTP140K-mediated in vivo selection

Foamy virus (FV) vectors are promising for hematopoietic stem cell (HSC) gene therapy but preclinical data on the clonal composition of FV vector transduced human repopulating cells is needed. Human CD34(+) human cord blood cells were transduced with an FV vector encoding a methylguanine methyltrans...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Gene Ther
Egile Nagusiak: Olszko, Miles E., Adair, Jennifer E., Linde, Ian, Rae, Dustin T., Trobridge, Patty, Hocum, Jonah D., Rawlings, David J., Kiem, Hans-Peter, Trobridge, Grant D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490015/
https://ncbi.nlm.nih.gov/pubmed/25786870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2015.20
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