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Efficacy and safety of a clinically relevant foamy vector design in human hematopoietic repopulating cells

BACKGROUND: Previous studies have shown that foamy viral (FV) vectors are a promising alternative to gammaretroviral and lentiviral vectors and insulators can improve FV vector safety. However, in a previous analysis of insulator effects on FV vector safety, strong viral promoters were used to elici...

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Détails bibliographiques
Publié dans:J Gene Med
Auteurs principaux: Everson, Elizabeth M., Hocum, Jonah D., Trobridge, Grant D.
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6368973/
https://ncbi.nlm.nih.gov/pubmed/29935087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jgm.3028
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