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Insulated Foamy Viral Vectors
Retroviral vector-mediated gene therapy is promising, but genotoxicity has limited its use in the clinic. Genotoxicity is highly dependent on the retroviral vector used, and foamy viral (FV) vectors appear relatively safe. However, internal promoters may still potentially activate nearby genes. We d...
Gespeichert in:
| Veröffentlicht in: | Hum Gene Ther |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Mary Ann Liebert, Inc.
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4800274/ https://ncbi.nlm.nih.gov/pubmed/26715244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2015.110 |
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