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Use of Cell and Genome Modification Technologies to Generate Improved “Off-the-Shelf” CAR T and CAR NK Cells

The broad success of adoptive immunotherapy to treat human cancer has resulted in a paradigm shift in modern medicine. Modification of autologous and allogenic immune cells with chimeric antigen receptors (CAR) designed to target specific antigens on tumor cells has led to production of CAR T and CA...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Morgan, Michael A., Büning, Hildegard, Sauer, Martin, Schambach, Axel
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7438733/
https://ncbi.nlm.nih.gov/pubmed/32903482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01965
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