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Use of Cell and Genome Modification Technologies to Generate Improved “Off-the-Shelf” CAR T and CAR NK Cells

The broad success of adoptive immunotherapy to treat human cancer has resulted in a paradigm shift in modern medicine. Modification of autologous and allogenic immune cells with chimeric antigen receptors (CAR) designed to target specific antigens on tumor cells has led to production of CAR T and CA...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Morgan, Michael A., Büning, Hildegard, Sauer, Martin, Schambach, Axel
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7438733/
https://ncbi.nlm.nih.gov/pubmed/32903482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01965
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