Chargement en cours...
Straightforward Generation of Ultrapure Off-the-Shelf Allogeneic CAR-T Cells
Here, we developed a straightforward methodology to generate TCRαβ negative (allogeneic) cells for CAR-T cell therapies. With an early and transient expression of an anti-CD3 CAR in the engineered donor T cells, we programmed these cells to self-eliminate the TCR+ cell population and obtained an ult...
Enregistré dans:
| Publié dans: | Front Bioeng Biotechnol |
|---|---|
| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2020
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7330105/ https://ncbi.nlm.nih.gov/pubmed/32671047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.00678 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|