TLR4-dependent adjuvant activity of Neisseria meningitidis lipid A

Por Zughaier, Susu, Steeghs, Liana, van der Ley, Peter, Stephens, David S.
Publicado em 2007

Outer membrane vesicles as platform vaccine technology

Por van der Pol, Leo, Stork, Michiel, van der Ley, Peter
Publicado no Biotechnol J (2015)

Lipopolysaccharide Engineering in Neisseria meningitidis: STRUCTURAL ANALYSIS OF DIFFERENT PENTAACYL LIPID A MUTANTS AND COMPARISON OF THEIR MODIFIED AGONIST PROPERTIES

Por Pupo, Elder, Hamstra, Hendrik-Jan, Meiring, Hugo, van der Ley, Peter
Publicado em 2014

The Omp85 protein of Neisseria meningitidis is required for lipid export to the outer membrane

Por Genevrois, Stéphanie, Steeghs, Liana, Roholl, Paul, Letesson, Jean-Jacques, van der Ley, Peter
Publicado em 2003

Agonists of Toll-Like Receptors 3, 4, 7, and 9 Are Candidates for Use as Adjuvants in an Outer Membrane Vaccine against Neisseria meningitidis Serogroup B

Por Fransen, Floris, Boog, Claire J., van Putten, Jos P., van der Ley, Peter
Publicado em 2007

Immunogenicity of Outer Membrane Proteins in a Lipopolysaccharide-Deficient Mutant of Neisseria meningitidis: Influence of Adjuvants on the Immune Response

Por Steeghs, Liana, Kuipers, Betsy, Hamstra, Hendrik Jan, Kersten, Gideon, van Alphen, Loek, van der Ley, Peter
Publicado em 1999

Coincorporation of LpxL1 and PagL Mutant Lipopolysaccharides into Liposomes with Neisseria meningitidis Opacity Protein: Influence on Endotoxic and Adjuvant Activity

Por Arenas, Jesús, van Dijken, Harry, Kuipers, Betsy, Hamstra, Hendrik Jan, Tommassen, Jan, van der Ley, Peter
Publicado em 2010

Modulating endotoxin activity by combinatorial bioengineering of meningococcal lipopolysaccharide

Por Zariri, Afshin, Pupo, Elder, van Riet, Elly, van Putten, Jos P. M., van der Ley, Peter
Publicado no Sci Rep (2016)

Modification of Lipid A Biosynthesis in Neisseria meningitidis lpxL Mutants: Influence on Lipopolysaccharide Structure, Toxicity, and Adjuvant Activity

Por van der Ley, Peter, Steeghs, Liana, Hamstra, Hendrik Jan, ten Hove, Jan, Zomer, Bert, van Alphen, Loek
Publicado em 2001

Opa(+) and Opa(−) Isolates of Neisseria meningitidis and Neisseria gonorrhoeae Induce Sustained Proliferative Responses in Human CD4(+) T Cells

Por Youssef, Abdel-Rahman, van der Flier, Michiel, Estevão, Silvia, Hartwig, Nico G., van der Ley, Peter, Virji, Mumtaz
Publicado em 2009

LOS oligosaccharide modification enhances dendritic cell responses to meningococcal native outer membrane vesicles expressing a non-toxic lipid A

Por Jones, Hannah E, Copland, Alastair, Hamstra, Hendrik Jan, Cohen, Jonathan, Brown, Jeremy, Klein, Nigel, van der Ley, Peter, Dixon, Garth
Publicado em 2014

Expression of the Lipopolysaccharide-Modifying Enzymes PagP and PagL Modulates the Endotoxic Activity of Bordetella pertussis

Por Geurtsen, Jeroen, Steeghs, Liana, Hamstra, Hendrik-Jan, ten Hove, Jan, de Haan, Alex, Kuipers, Betsy, Tommassen, Jan, van der Ley, Peter
Publicado em 2006

Relative Immunogenicity of PorA Subtypes in a Multivalent Neisseria meningitidis Vaccine Is Not Dependent on Presentation Form

Por Luijkx, Thomas A., van Dijken, Harry, Hamstra, Hendrik-Jan, Kuipers, Betsy, van der Ley, Peter, van Alphen, Loek, van den Dobbelsteen, Germie
Publicado em 2003

Llama Single-Chain Antibody That Blocks Lipopolysaccharide Binding and Signaling: Prospects for Therapeutic Applications

Por El Khattabi, Mohamed, Adams, Hendrik, Heezius, Erik, Hermans, Pim, Detmers, Frank, Maassen, Bram, van der Ley, Peter, Tommassen, Jan, Verrips, Theo, Stam, Jord
Publicado em 2006

The Structure of Neisseria meningitidis Lipid A Determines Outcome in Experimental Meningococcal Disease

Por Fransen, Floris, Hamstra, Hendrik Jan, Boog, Claire J., van Putten, Jos P., van den Dobbelsteen, Germie P. J. M., van der Ley, Peter
Publicado em 2010

Antigen sparing with adjuvanted inactivated polio vaccine based on Sabin strains

Por Westdijk, Janny, Koedam, Patrick, Barro, Mario, Steil, Benjamin P., Collin, Nicolas, Vedvick, Thomas S., Bakker, Wilfried A.M., van der Ley, Peter, Kersten, Gideon
Publicado em 2013

Differential Activation of Human and Mouse Toll-Like Receptor 4 by the Adjuvant Candidate LpxL1 of Neisseria meningitidis

Por Steeghs, Liana, Keestra, A. Marijke, van Mourik, Andries, Uronen-Hansson, Heli, van der Ley, Peter, Callard, Robin, Klein, Nigel, van Putten, Jos P. M.
Publicado em 2008

Cysteine Depletion Causes Oxidative Stress and Triggers Outer Membrane Vesicle Release by Neisseria meningitidis; Implications for Vaccine Development

Por van de Waterbeemd, Bas, Zomer, Gijsbert, van den IJssel, Jan, van Keulen, Lonneke, Eppink, Michel H., van der Ley, Peter, van der Pol, Leo A.
Publicado em 2013

Dendritic Cell Activation and Cytokine Production Induced by Group B Neisseria meningitidis: Interleukin-12 Production Depends on Lipopolysaccharide Expression in Intact Bacteria

Por Dixon, Garth L. J., Newton, Phillippa J., Chain, Benjamin M., Katz, David, Andersen, Svein Rune, Wong, Simon, van der Ley, Peter, Klein, Nigel, Callard, Robin E.
Publicado em 2001

Working Mechanism of Immunoglobulin A1 (IgA1) Protease: Cleavage of IgA1 Antibody to Neisseria meningitidis PorA Requires De Novo Synthesis of IgA1 Protease

Por Vidarsson, Gestur, Overbeeke, Natasja, Stemerding, Annette M., van den Dobbelsteen, Germie, van Ulsen, Peter, van der Ley, Peter, Kilian, Mogens, van de Winkel, Jan G. J.
Publicado em 2005