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TLR4-dependent adjuvant activity of Neisseria meningitidis lipid A
The adjuvant activity of Neisseria meningitidis serogroup B lipopoly(oligo)saccharide (LOS) from wild-type and genetically-defined LOS mutants and unglycosylated meningococcal lipid A was assessed in C3H/HeN and C3H/HeJ mice. Meningococcal lipid A, a weak agonist for TLR4/MD-2 in human macrophages,...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2722072/ https://ncbi.nlm.nih.gov/pubmed/17466419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2007.03.029 |
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