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Antigen sparing with adjuvanted inactivated polio vaccine based on Sabin strains

Six different adjuvants, each in combination with inactivated polio vaccine (IPV) produced with attenuated Sabin strains (sIPV), were evaluated for their ability to enhance virus neutralizing antibody titers (VNTs) in the rat potency model. The increase of VNTs was on average 3-, 15-, 24-fold with a...

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Detalhes bibliográficos
Main Authors: Westdijk, Janny, Koedam, Patrick, Barro, Mario, Steil, Benjamin P., Collin, Nicolas, Vedvick, Thomas S., Bakker, Wilfried A.M., van der Ley, Peter, Kersten, Gideon
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570672/
https://ncbi.nlm.nih.gov/pubmed/23313617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2012.12.076
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