Antigen sparing with adjuvanted inactivated polio vaccine based on Sabin strains

Six different adjuvants, each in combination with inactivated polio vaccine (IPV) produced with attenuated Sabin strains (sIPV), were evaluated for their ability to enhance virus neutralizing antibody titers (VNTs) in the rat potency model. The increase of VNTs was on average 3-, 15-, 24-fold with a...

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Main Authors: Westdijk, Janny, Koedam, Patrick, Barro, Mario, Steil, Benjamin P., Collin, Nicolas, Vedvick, Thomas S., Bakker, Wilfried A.M., van der Ley, Peter, Kersten, Gideon
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570672/
https://ncbi.nlm.nih.gov/pubmed/23313617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2012.12.076
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