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Development of Thermostable Lyophilized Inactivated Polio Vaccine

PURPOSE: The aim of current study was to develop a dried inactivated polio vaccine (IPV) formulation with minimal loss during the drying process and improved stability when compared with the conventional liquid IPV. METHODS: Extensive excipient screening was combined with the use of a Design of Expe...

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Autors principals: Kraan, Heleen, van Herpen, Paul, Kersten, Gideon, Amorij, Jean-Pierre
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197379/
https://ncbi.nlm.nih.gov/pubmed/24760448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-014-1359-6
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